SharpBetz
NCAAB

Villanova Wildcats vs DePaul Blue Demons

Thursday, March 5, 2026

Matchup Analysis

This NCAAB matchup features Villanova Wildcats (22-7 (13-3)) traveling to take on DePaul Blue Demons (16-13 (11-5)) at Wintrust Arena, Chicago, IL. The Villanova hold a clear statistical edge this season, outperforming the DePaul by 4.4 points per game in scoring margin. That differential will be a key factor in this matchup. On offense, DePaul averages 71.2 points per game, which exceeds what the Villanova defense typically allows (70.8 PPG). That mismatch could give the home side opportunities to exploit. The Villanova offense puts up 77.2 PPG and faces a DePaul defense allowing 69.2 PPG. The visitors have the offensive firepower to stay in this one. Home court advantage is worth approximately 3.5 points in NCAAB, and DePaul will look to leverage their home crowd. Our model sees this as essentially a coin-flip game, projecting just a 0.1-point margin. Expect a tight finish. The 68% confidence interval ranges from DePaul winning by 13 to losing by 13. The market has this game at +3.5, but our model sees value on DePaul with a 3.6-point edge. Our line: DePaul -0.1. Combined with the total projection of 148 versus the market line of 135.5, there are opportunities to find value on both sides of this matchup.

Team Comparison

VILL Villanova
Stat
DEP DePaul
22-7 (13-3)
Record
16-13 (11-5)
Last 10
77.2
PPG
71.2
70.8
Opp PPG
69.2

Current Odds

Team Moneyline Spread Total
VILL Villanova Wildcats
-175 -3.5 O 135.5
DEP DePaul Blue Demons
+145 +3.5 U 135.5
Source: Draft Kings Updated: Mar 4, 5:45 AM
Opening line: +3.5 / O/U 135.5

Model Projection

Team Moneyline Spread Total
VILL Villanova Wildcats
-103 +0.1 O 148.3
DEP DePaul Blue Demons
+103 -0.1 U 148.3
Source: Model Updated: Mar 4, 5:45 AM

Our Picks

Spread
DePaul (opened at +3.5)
54% Confidence

Play to -0.8

Total
Over (opened at 135.5)
75% Confidence

Play to 147.6

Recent Trends

DePaul enters at 16-13 (11-5), hovering around the .500 mark. They've shown flashes of strong play but haven't been able to sustain consistency. At home, they'll look to put together a complete performance and build momentum. Villanova comes in with an impressive 22-7 (13-3) record. They've been among the best teams in their conference and are playing with the confidence of a squad that expects to win. Road games can be tricky, but this team has the poise to handle hostile environments. When these teams meet, the home team typically has the edge given the crowd advantage and familiarity factor. The team that controls tempo and limits turnovers will likely dictate the outcome of this matchup.

Matchup Edges

DePaul

Advantages

  • Home court advantage and crowd support
  • Familiarity with home venue and routines

Disadvantages

  • Potential for inconsistency in key moments

Villanova

Advantages

  • Strong 22-7 (13-3) overall record this season
  • Potent offense averaging 77.2 PPG
  • Road underdog motivation — play with less pressure

Disadvantages

  • Playing on the road without home crowd support
  • Road fatigue and travel can impact energy levels